personal health analysis
 





A treatable disease?

Solution You need to learn what you can do today to make sure that you live long enough to take advantage of all the future medical innovations now in the works.

There are many ongoing projects that promise to solve, or at least help with our problems of aging. One is from a team of South Korean scientists. They report that they have created a newly-synthesized molecule, named CGK733 that can make cells younger.

"All cells face an inevitable death as they age. On this path, cells became lethargic and in the end stop dividing but we witnessed that CGK733 can block the process," Prof. Kim Tae-kook reported.

He further stated: "We also found the synthetic compound can reverse aging, by revitalizing already-lethargic cells. Theoretically, this can give youth to the elderly via rejuvenating cells."

Kim expects that the CGK733-empowered drugs that keep cells youthful far beyond their normal life span will be commercialized in less than 10 years.

"We have the magnet-associated technology to identify molecular targets inside living cells, which allowed us to examine the mechanisms of CGK733 directly," Kim said.

"Unlike other research teams that must make candidate materials for drugs without being able to see their intra-cell activities; we know the precise mechanism of CGK733. So we have the better chance of making a success of the substance," he continued.

Researchers at The Wistar Institute have defined a key target of an evolutionarily conserved protein that regulates the process of aging. The study provides fundamental knowledge about key mechanisms of aging that could point toward new anti-aging strategies and cancer therapies.

Scientists had long known that a class of proteins called sirtuins promotes fitness and longevity in most organisms ranging from single-celled yeast to mammals. At the cellular level, sirtuins protect genome integrity, enhance resistance to adverse stresses, and antagonize senescence. However, the underlying molecular mechanisms have remained poorly understood.

The Wistar team, led by senior author Shelley Berger, Ph.D., Hilary Koprowski Professor at The Wistar Institute, demonstrated for the first time a molecular target for a member of this class, Sir2, in regulation of aging in yeast cells.

Aging saps our strength and ability to enjoy life, cripples us, and eventually kills us. Tens of millions die from age-related conditions each and every year. Comparatively few people know that degenerative aging can be slowed with diet and lifestyle choices, medicines and nutracuetials.
 
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Article details
Article ID: 39
Category: Aging is a treatable disease
Date added: 2009-10-03 17:13:13
Views: 20
Rating (Votes): Article rated 3.0/5.0 (2)

 
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